Method of imaging a random medium

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United States of America Patent

PATENT NO 5137355
SERIAL NO

07363075

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Abstract

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A non-invasive medical imaging technique capable of evaluating, in situ, the oxygenation state of body tissues (e.g., by measuring the spectral properties of heme proteins) is described. The technique is based on the measurement of scattered radiation in the near-infrared region (NIR), where significant penetration into body tissues occurs. The disclosed technique employs a multi-wavelength collimated source and a collimated receiver and performs a positional and angular scan of the scattered radiation for each position of the incident beam. The resultant data is evaluated by employing imaging schemes which give differential weights to the contribution of various volume elements (voxels) in the medium to the detector response. A three-dimensional spectroscopic image of the target medium is determined by considering the contribution of the various volume elements for each source-detector configuration and position of the incident beam at various frequencies. These measurements, in an imaging mode, yield vital physiological information while being, for example, a sensitive indicator of subtle physiological stress caused by disease or trauma.

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Patent Owner(s)

Patent OwnerAddress
RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK THE1576 SWEEET HOME ROAD SUITE 111 AMHERST NY 14228

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aronson, Raphael Great Neck, NY 1 85
Barbour, Randall L Westbury, NY 24 575
Lubowsky, Jack Merrick, NY 2 92

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