Process for the production of human tissue plasminogen activator and cell strain useful therefor

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United States of America Patent

PATENT NO 5139939
SERIAL NO

07219364

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Abstract

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Human tissue plasminogen activator is produced by culturing a human rhabdomyosarcoma-derived cell, KYM-SF, in a medium, followed by purification of single-chain and/or double-chain human tissue plasminogen activator from the medium.

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Patent Owner(s)

Patent OwnerAddress
MEIJI MILK PRODUCTS CO LTD76 NISHISAKURA-CHO MINAMI-KU NAGOYA-SHI AICHI JAPAN 2-3-6 KYOBASHI CHUO-KU TOKYO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hamaguchi, Yoshitaka Odawara, JP 15 155
Miyahara, Nichinori Odawara, JP 1 2
Ohashi, Akira Yokohama, JP 27 162
Oyama, Yoshio Kanagawa, JP 12 68
Shiomichi, Toru Odawara, JP 1 2

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