Purification of Q Beta replicase

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United States of America Patent

PATENT NO 5141857
SERIAL NO

07364306

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A process of producing highly pure, Q Beta replicase having a high level of activity is described. The present process allows isolation of Q Beta replicase from recombinant bacteria containing a clone of a phage DNA encoding the 65,000 weight subunit of Q Beta replicase. The present process provides an efficient method for producing pure Q Beta replicase which can readily be scaled up to commercial production levels.

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Patent Owner(s)

Patent OwnerAddress
AMOCO CORPORATION AN IN CORPCHICAGO IL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
DiFrancesco, Robert A Auburn, MA 4 57

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