Method of preparing polyvinyl alcohol gel

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 5141973
SERIAL NO

07457942

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method of preparing a polyvinyl alcohol hydrogel contains the steps of charging an aqueous solution of a polyvinyl alcohol having a degree of hydrolysis of not less than 95 mol % and an average polymerization degree of not less than 500 into a container, the aqueous solution containing the polyvinyl alcohol in a concentration of not less than 5 wt. %, cooling the aqueous solution of the polyvinyl alcohol at a temperature of from -(minus) 9.degree. C. to - (minus) 3.degree. C., subjecting the aqueous solution of the polyvinyl alcohol to physical stimulation, and then maintaining the aqueous solution of the polyvinyl alcohol at a temperature of from - (minus) 5.degree. C. to + (plus) 5.degree. C. The polyvinyl alcohol hydrogel may be contained in a plastic container. An MRI phanton is composed of the plastic container containing such polyvinyl alcohol hydrogel.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
NIPPON MITSUBISHI OIL CORPORATIONTOKYO144

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kobayashi, Tomokazu Kawasaki, JP 21 70
Morihiro, Toshio Yokohama, JP 1 19

Cited Art Landscape

Patent Info (Count) # Cites Year
 
TIORCO, INC. (1)
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SHIN-ETSU CHEMICAL CO., LTD. (1)
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Rhone-Poulenc Chimie (1)
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CITIES SERVICE OIL AND GAS CORPORATION (1)
* 4939203 Gel for retarding water flow 6 1988
 
KABUSHIKI KAISHA TOSHIBA (1)
* 4774957 Material for diagnosis by nuclear magnetic resonance imaging 39 1987
 
NIPPON OIL COMPANY, LIMITED (3)
* 4472542 Freeze-dried polyvinyl alcohol gel 64 1983
* 4734097 Medical material of polyvinyl alcohol and process of making 91 1985
* 4916170 Process for making skin marker 36 1988
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (2)
6650934 Polymeric foam reservoirs for an electrotransport delivery device 5 1997
* 2007/0208,280 Ultrasound bandage 7 2007
 
COOPERSURGICAL, INC. (3)
* 6117072 Plastic stay assembly for use with MRI and X-ray imaging systems 11 1998
* 5964698 Sliding hook assembly for use with a surgical retractor stay apparatus and methods for use 33 1999
6190312 Variable geometry retractor and disposable retractor stay clips and method of use 28 1999
 
STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (1)
* 6224969 Optical phantom suitable for stimulating the optical properties of biological material and a method of producing said phantom 35 1998
 
ALZA CORPORATION (2)
6246904 Electrotransport drug delivery reservoirs containing inert fillers 15 1997
* 6039977 Pharmaceutical hydrogel formulations, and associated drug delivery devices and methods 21 1997
 
CARTICEPT MEDICAL, INC. (2)
8038920 Methods of producing PVA hydrogel implants and related devices 5 2007
* 2007/0179,622 METHODS OF PRODUCING PVA HYDROGEL IMPLANTS AND RELATED DEVICES 18 2007
 
MIMEDX GROUP, INC. (2)
8603171 Spinal disc implants with flexible keels and methods of fabricating implants 6 2007
* 2007/0179,621 SPINAL DISC IMPLANTS WITH FLEXIBLE KEELS AND METHODS OF FABRICATING IMPLANTS 29 2007
 
TAKEDA CHEMICAL INDUSTRIES, LTD. (1)
* 5346935 Hydrogel 26 1993
 
GEORGIA TECH RESEARCH CORPORATION (8)
8002830 Surface directed cellular attachment 8 2005
7910124 Load bearing biocompatible device 9 2005
* 2007/0299,540 METHODS OF MAKING MEDICAL IMPLANTS OF POLY (VINYL ALCOHOL) HYDROGEL 10 2007
8142808 Method of treating joints with hydrogel implants 6 2008
7682540 Method of making hydrogel implants 49 2008
8318192 Method of making load bearing hydrogel implants 4 2008
8895073 Hydrogel implant with superficial pores 1 2011
8486436 Articular joint implant 2 2012
 
CARTIVA, INC. (2)
9155543 Tapered joint implant and related tools 1 2012
9526632 Methods of repairing a joint using a wedge-shaped implant 0 2015
* Cited By Examiner