Process for cross-linking collagenous material and resulting product
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United States of America Patent
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Sep 15, 1992
Issued Date -
N/A
app pub date -
Jul 30, 1990
filing date -
Aug 2, 1987
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
The present invention relates to a process for cross-linking a proteinaceous material. The process comprises: i) soaking the material to be cross-linked in an aqueous solution of high osmolality; ii) incubating the material in an aqueous buffer including an amount of a photooxidative catalyst sufficient to catalyze photooxidation of the material; and iii) irradiating the material and the catalyst of step (i) with light that includes a range of wavelengths selectively absorbed by the catalyst. Irradiation is effected under conditions such that cross-linking of the material occurs. In a further embodiment, the present invention relates to a cross-linked product produced by the above-described method.
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