Resorbable bioactive calcium phosphate cement
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United States of America Patent
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Sep 22, 1992
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N/A
app pub date -
Jan 10, 1991
filing date -
Jan 10, 1991
priority date (Note) -
Expired
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Abstract
This invention provides a calcium phosphate cement with relatively high surface pH which is very beneficial from the biocompatibility point of view. When calcium phosphate salts react with an acidic reagent to form cement, it normally involves the dissolution and recrystallization process. The acidity of the setting cements depends strongly on the nature of the calcium phosphate salt used, the acidity of the setting reagent, and the reaction rate. The present invention uses high alkaline calcium phosphate ceramics such as tetracalcium phosphate alone or together with calcium phosphate ceramics such as .alpha.-tricalcium phosphate as base cementing powder to increase the surface pH of the setting cement.
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