Solid phase analytical device and method for using same
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United States of America Patent
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Sep 22, 1992
Issued Date -
N/A
app pub date -
May 21, 1990
filing date -
Oct 4, 1985
priority date (Note) -
Expired
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Abstract
A novel material and device useful in solid-phase binding assays to determine the presence or amount of an analyte in a test sample, particularly antigens or antibodies, is disclosed. The material comprises a porous matrix of fibers and a plurality of substantially spherical, solid particles having an average diameter of from about 0.1 to about 5 microns. The particles are retained and immobilized upon the fibers of the matrix. Preferably, the particles have on their surfaces a substance capable of reaction with the analyte in the sample, and the average diameter of the particles is less than the average pore size of the matrix. The device, in a preferred embodiment, comprises a substantially planar layer of the described material.
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