Aldose reductase inhibitor

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United States of America Patent

PATENT NO 5155259
SERIAL NO

07742352

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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An aldose reductase inhibitor, comprising a compound of the formula (I) ##STR1## or a pharmaceutically acceptable salt thereof as the effective component, in which R is lower alkyl or cyclohexylmethyl and n is 2 or 3. The compounds of formula (I) and salts thereof according to the invention exhibit a superior aldose reductase inhibiting activity with simultaneous high stability, so that they are useful for the prevention and therapy of diabetic complications.

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Patent Owner(s)

Patent OwnerAddress
ASAHI KASEI KOGYO KABUSHIKI KAISHAOSAKA JAPAN OSAKA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Asahi, Akira Shizuoka, JP 6 42
Kuno, Kouichi Shizuoka, JP 2 22
Shoda, Motoshi Shizuoka, JP 13 92
Suzuki, Yukio Shizuoka, JP 157 1312
Yaginuma, Satoshi Shizuoka, JP 10 82
Yaso, Masao Shizuoka, JP 13 56

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