Insulin derivatives and pharmaceutical preparations containing these derivatives
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United States of America Patent
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Oct 20, 1992
Issued Date -
N/A
app pub date -
Dec 20, 1990
filing date -
Mar 15, 1985
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Insulin derivatives in which from two to four amino acid residues of positions, A4, A17, B13 and B21 comprise an uncharged side chain and pharmaceutical preparations containing these insulin derivatives. The disclosed insulin derivatives and preparations possess protracted insulin activity. The protracted insulin activity is relatively insensitive to tryptic activity.
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