Synergistic tumor therapy with combinations of biologically active anti-tumor antibodies and chemotherapy
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United States of America Patent
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Nov 24, 1992
Grant Date -
N/A
app pub date -
May 22, 1990
filing date -
May 22, 1990
priority date (Note) -
Expired
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Abstract
The present invention relates to the use of combinations of antibody therapy and chemotherapy in the treatment of malignant disease. More particularly, the invention relates to novel methods of treating patients who have malignant disease and who have shown an unresponsiveness to treatment with standard chemotherapy regimens by administering to those patients (i) an antibody that binds to the malignant cells of the patient and (ii) a chemotherapeutic agent. According to particular embodiments of the invention, anti-glycolipid antibodies are administered to patients who are subsequently treated with standard chemotherapy regimens.
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