Wound healing agents derived from platelets
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United States of America Patent
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Nov 24, 1992
Issued Date -
N/A
app pub date -
May 18, 1990
filing date -
Nov 29, 1984
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Platelet enriched plasma is produced from blood. The platelets are activated by thrombm which causes the release of platelet derived growth and angiogenesis factors. A carrier such as a microcrystalline collagen is added to produce a wound treating salve. The compound is applied directly to wounds and initiates healing in non-healing wounds as well as accelerating normal wound healing by increasing vascularization, stimulating fibroblast mitosis and migration and increasing collagen synthesis by fibroblasts. The process of treatment involves the use of a composition containing the materials released by platelets during the platelet release reaction.
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