Method for enhancing the systemic delivery of dextromethorphan for the treatment of neurological disorders
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United States of America Patent
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Nov 24, 1992
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N/A
app pub date -
Jun 17, 1991
filing date -
Jun 17, 1991
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Abstract
A method for enhancing the systemic delivery of dextromethorphan for the treatment of a neurological disorder resulting in injury to nervous tissue, which comprises administering to a patient suffering from the disorder an amount of a cytochrome P450IID6 enzyme inhibitor, sufficient to block dextromethorphan metabolism, and an amount of dextromethorphan sufficient to treat the neurological disorder. Quinidine is particularly suitable for use in the method of the invention.
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