Buoyant controlled release powder formulation
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United States of America Patent
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Dec 8, 1992
Grant Date -
N/A
app pub date -
Oct 23, 1991
filing date -
Oct 23, 1991
priority date (Note) -
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status (Latency Note)
Importance
Abstract
A buoyant controlled release pharmaceutical powder formulation is provided which may be filled into capsules and releases a pharmaceutical of a basic character at a controlled rate regardless of the pH of the environment, which formulation includes a basic pharmaceutical, up to about 45% by weight of a pH dependent polymer which is a salt of alginic acid, such as sodium alginate, up to about 35% by weight of a pH-independent hydrocarbon gelling agent having a viscosity of up to about 100,000 centipoises in 2% solution at 20.degree. C. and excipients.
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