Directly compressible granules having improved flow properties

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United States of America Patent

PATENT NO 5169645
SERIAL NO

07429858

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Abstract

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Directly compressible, wax-containing granules having improved flow properties are obtained when waxes are admixed in the melt with certain flow improving additives, followed by cooling and granulation of the admixture. In certain embodiments of the invention, only the wax itself melts in the melt combination of the wax(es) and additives(s), and in other cases both the wax(es) and the additives(s) will both melt. In either case, the melt combination of the wax(es) with the additive(s) yields, upon cooling and granulation, a wax-containing particulate drug diluent having improved and unexpected flow properties.

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Patent Owner(s)

Patent OwnerAddress
DUQUESNE UNIVERSITY OF THE HOLY GHOST A CORP OF PAPITTSBURGH PA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Nambiar, Jyothi S Pittsburgh, PA 1 280
Shukla, Atul J Memphis, TN 15 708
Vattanasiri, Anumontri Bangkok, TH 1 280

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