Method of enhancing the regeneration of injured nerves and adhesive pharamaceutical formulation therefor
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United States of America Patent
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Dec 22, 1992
Grant Date -
N/A
app pub date -
Oct 5, 1990
filing date -
Oct 5, 1990
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
The regeneration of injured nerves is enhanced by supplying collagenase to the zone of injury of the nerve. Growth of nerve sprouts over the zone of injury is aided by the presence of effective amounts of collagenase during the regeneration process. If the nerve has been severed, collagenase is supplied to the ends of the proximal and distal stumps. A nerve graft may be interposed between the stumps. Natural fibrin has been used as glue to join nerve stumps, and collagenase is effective when used in admixture with fibrin.
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