Metal-free buffer for ion selective electrode-based assays
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United States of America Patent
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Dec 29, 1992
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N/A
app pub date -
Jun 8, 1990
filing date -
Jun 8, 1990
priority date (Note) -
Expired
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Abstract
A heavy metal-free composition and its method of use in an ion selective electrode-based assay are disclosed. The heavy metal-free composition includes a borate compound and an alkalinity adjusting compound, and is used to dilute a test sample; buffer the test sample; and substantially reduce the effects of interferents present in the test sample on the ion selective electrode-based assay. The heavy metal-free composition and its method of use are especially useful in an ion selective electrode-based assay for carbonate ion concentration in a test sample, like blood serum, blood plasma, urine or cerebrospinal fluid.
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