Medical grade adhesives and their preparation
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United States of America Patent
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Dec 29, 1992
Grant Date -
N/A
app pub date -
Jan 22, 1992
filing date -
Jan 22, 1992
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Crosslinked hydrogel polymers are made by reacting a disubstituted aliphatic diamine of the general formula (I) or (XI) as given in the specification, with one or more diepoxides having the general formula (II), also as given in the specification, and subjecting the resulting non-crosslinked polymer having repeating units of the formula III or XIII to crosslinking conditions to produce the desired crosslinked hydrogel polymer. Hydrogel polymers thus produced are highly hydrophilic with a high degree of water uptake and a high equilibrium water content. In addition, these hydrogel polymers are highly absorptive of fluids and are adhesive when applied to dry surfaces but not when applied to wet surfaces. The hydrogel polymers are useful in wound dressings.
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