Detection of viruses by amplification and hybridization

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United States of America Patent

PATENT NO 5176995
SERIAL NO

07394145

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Abstract

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The presence or absence of a nucleic acid sequence associated with one or more related viruses in a sample containing one or more nucleic acids and suspected of containing such sequence can be detected by amplifying the sequence using primers to form extension products as templates and detecting the amplified product if it is present. This may be accomplished by adding a labeled hybridization probe to the amplified product either free in solution or after immobilization on a solid support. Preferably the virus constitutes AIDs viruses and hepadnaviruses.

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Patent Owner(s)

Patent OwnerAddress
ROCHE MOLECULAR SYSTEMS INC4300 HACIENDA DRIVE PLEASANTON CA 94588

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ehrlich, Henry A Oakland, CA 1 117
Kwok, Shirley Y San Ramon, CA 8 583
Mack, David H Berkeley, CA 37 1137
Mullis, Kary B LaJolla, CA 32 16824
Sninsky, John J El Sobrante, CA 9 601

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