Antimicrobial quinolonyl lactam esters
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United States of America Patent
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Jan 19, 1993
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N/A
app pub date -
Apr 29, 1991
filing date -
Oct 24, 1988
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Abstract
Antimicrobial quinolonyl lactam esters comprising a lactam-containing moiety linked, by an ester group, to the 3-carboxy group of a quinolone moiety. These compounds are of the formula: ##STR1## wherein (1) R.sup.3, R.sup.4, and R.sup.5, together with bonds 'a' and 'b', form certain lactam-containing moieties similar to those known in the art to have antimicrobial activity; and (2) A.sup.2, A.sup.2, A.sup.3, R.sup.7, R.sup.8, and R.sup.9 form any of a variety of quinolone or naphthyridine structures similar to those known in the art to have antimicrobial activity.
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