US Patent No: 5,192,311

Number of patents in Portfolio can not be more than 2000

Medical implant and method of making

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Importance

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Abstract

The method of generating a homograft includes preparing a prosthesis composed of a tubular substrate. The substrate is open at each end to permit blood to flow along the length of the substrate inside wall. The substrate is selected to have at least one thrombogenic surface or a thrombogenic mesh material supported by the substrate. The prosthesis is inserted in the lumen of a blood vessel, either a vein or artery, of a living body and anchored in the lumen of the vessel to prevent the substrate from moving along the vessel with the blood flow. The body generates collagenous growth on the thrombogenic surface of the substrate while the substrate is freely suspended in the blood flow of the vessel. The substrate is then removed from the vessel after which a tubular homograft of collagenous tissue is removed from the substrate.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ANGEION CORPORATIONPLYMOUTH, MN66

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adams, Theodore P Edina, MN 66 3370
Kane, Lawrence M Roseville, MN 10 560
King, Wendell L Pillager, MN 9 565

Cited Art

Patent Info (Count) # Cites Year
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (1)
4,539,716 Fabrication of living blood vessels and glandular tissues 84 1981
 
WILKRACHT PTY. LTD (1)
4,319,363 Vascular prostheses 96 1979

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
ADVANCED CARDIOVASCULAR SYSTEMS, INC. (113)
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5,344,426 Method and system for stent delivery 354 1993
5,441,515 Ratcheting stent 446 1993
5,456,667 Temporary stenting catheter with one-piece expandable segment 345 1993
5,507,768 Stent delivery system 269 1993
5,458,615 Stent delivery system 292 1993
5,649,977 Metal reinforced polymer stent 400 1994
5,707,385 Drug loaded elastic membrane and method for delivery 233 1994
5,637,113 Polymer film for wrapping a stent structure 361 1994
5,569,295 Expandable stents and method for making same 328 1995
5,632,840 Method of making metal reinforced polymer stent 190 1995
5,618,299 Ratcheting stent 236 1995
5,782,855 Stent delivery system 100 1996
5,649,952 Expandable stents and method for making same 185 1996
5,700,286 Polymer film for wrapping a stent structure 521 1996
6,019,777 Catheter and method for a stent delivery system 38 1997
6,776,792 Coated endovascular stent 28 1997
5,916,234 Expandable stents and method for making same 68 1997
6,136,011 Stent delivery system and method of use 18 1998
6,113,607 Method of delivering a stent 47 1998
6,464,723 Radiopaque stents 4 1999
6,488,694 Stent delivery system 105 1999
6,217,586 Catheter and method for a stent delivery system 32 1999
6,585,757 Endovascular stent with radiopaque spine 7 1999
6,334,868 Stent cover 21 1999
6,605,114 Heparin delivery method 26 1999
6,602,287 Stent with anti-thrombogenic coating 28 1999
6,251,136 Method of layering a three-coated stent using pharmacological and polymeric agents 276 1999
6,702,849 Method of processing open-celled microcellular polymeric foams with controlled porosity for use as vascular grafts and stent covers 40 1999
6,527,801 Biodegradable drug delivery material for stent 243 2000
6,309,412 Expandable stents and method for making same 43 2000
6,652,579 Radiopaque stent 50 2000
6,432,133 Expandable stents and method for making same 68 2000
6,641,607 Double tube stent 61 2000
6,596,022 Expandable stents and method for making same 36 2001
6,773,455 Stent with reinforced struts and bimodal deployment 15 2001
7,201,940 Method and apparatus for thermal spray processing of medical devices 4 2001
6,485,511 Expandable stents and method for making same 38 2001
8,123,799 Modified implantable device surface and a method of making the same 0 2001
7,144,422 Drug-eluting stent and methods of making the same 15 2002
6,899,729 Stent for treating vulnerable plaque 37 2002
7,316,710 Flexible stent 9 2002
7,163,715 Spray processing of porous medical devices 52 2002
7,105,018 Drug-eluting stent cover and method of use 50 2002
6,896,697 Intravascular stent 56 2002
7,470,283 Biodegradable drug delivery material for stent 5 2003
7,390,333 Biodegradable drug delivery material for stent 8 2003
6,875,229 Stent and catheter assembly and method for treating bifurcations 9 2003
7,258,891 Stent mounting assembly and a method of using the same to coat a stent 13 2003
6,908,479 Expandable stents and method for making same 6 2003
6,689,159 Expandable stents and method for making same 34 2003
7,186,789 Bioabsorbable, biobeneficial polyester polymers for use in drug eluting stent coatings 7 2003
7,285,304 Fluid treatment of a polymeric coating on an implantable medical device 17 2003
6,955,688 Stent and catheter assembly and method for treating bifurcations 50 2003
7,435,255 Drug-eluting stent and methods of making 2 2003
7,198,675 Stent mandrel fixture and method for selectively coating surfaces of a stent 46 2003
6,896,699 Stent and catheter assembly and method for treating bifurcations 53 2003
7,258,697 Stent with anchors to prevent vulnerable plaque rupture during deployment 8 2003
7,563,324 System and method for coating an implantable medical device 19 2003
7,699,890 Medicated porous metal prosthesis and a method of making the same 1 2004
7,553,377 Apparatus and method for electrostatic coating of an abluminal stent surface 5 2004
7,329,366 Method of polishing implantable medical devices to lower thrombogenecity and increase mechanical stability 5 2004
7,077,860 Method of reducing or eliminating thrombus formation 13 2004
8,172,897 Polymer and metal composite implantable medical devices 0 2004
7,297,159 Selective coating of medical devices 3 2004
7,229,471 Compositions containing fast-leaching plasticizers for improved performance of medical devices 55 2004
8,173,062 Controlled deformation of a polymer tube in fabricating a medical article 0 2004
8,043,553 Controlled deformation of a polymer tube with a restraining surface in fabricating a medical article 1 2004
7,632,307 Abluminal, multilayer coating constructs for drug-delivery stents 3 2004
7,758,881 Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device 1 2005
7,381,048 Stents with profiles for gripping a balloon catheter and molds for fabricating stents 2 2005
7,513,907 Expandable stents and method for making same 1 2005
7,291,166 Polymeric stent patterns 10 2005
7,875,283 Biodegradable polymers for use with implantable medical devices 2 2005
7,622,070 Method of manufacturing an implantable polymeric medical device 5 2005
7,875,233 Method of fabricating a biaxially oriented implantable medical device 3 2005
7,658,880 Polymeric stent polishing method and apparatus 1 2005
7,297,758 Method for extending shelf-life of constructs of semi-crystallizable polymers 1 2005
7,476,245 Polymeric stent patterns 3 2005
7,867,547 Selectively coating luminal surfaces of stents 0 2005
7,951,185 Delivery of a stent at an elevated temperature 2 2006
7,989,018 Fluid treatment of a polymeric coating on an implantable medical device 1 2006
8,003,156 Rotatable support elements for stents 1 2006
7,761,968 Method of crimping a polymeric stent 4 2006
7,959,940 Polymer-bioceramic composite implantable medical devices 1 2006
7,731,890 Methods of fabricating stents with enhanced fracture toughness 0 2006
8,333,000 Methods for improving stent retention on a balloon catheter 0 2006
7,794,776 Modification of polymer stents with radiation 2 2006
7,740,791 Method of fabricating a stent with features by blow molding 0 2006
7,998,404 Reduced temperature sterilization of stents 0 2006
7,757,543 Radio frequency identification monitoring of stents 1 2006
7,794,495 Controlled degradation of stents 3 2006
7,886,419 Stent crimping apparatus and method 0 2006
7,416,558 Drug-eluting stent cover and method of use 34 2006
7,413,574 Drug-eluting stent cover method of use 4 2006
8,128,687 Drug-eluting stent with filament strands 0 2006
7,923,022 Degradable polymeric implantable medical devices with continuous phase and discrete phase 1 2006
7,842,737 Polymer blend-bioceramic composite implantable medical devices 1 2006
7,514,122 Method and apparatus for spray processing of porous medical devices 4 2006
7,312,299 Bioabsorbabl, biobeneficial polyester polymers for stent coatings 1 2006
7,301,001 Bioabsorbable, biobeneficial polyester polymers for stent coatings 2 2006
8,197,879 Method for selectively coating surfaces of a stent 0 2007
7,604,700 Stent mandrel fixture and method for selectively coating surfaces of a stent 1 2007
7,662,326 Compositions containing fast-leaching plasticizers for improved performance of medical devices 1 2007
7,955,381 Polymer-bioceramic composite implantable medical device with different types of bioceramic particles 0 2007
7,753,950 Stent and catheter assembly and method for treating bifurcations 1 2007
8,109,994 Biodegradable drug delivery material for stent 1 2008
7,967,998 Method of polishing implantable medical devices to lower thrombogenecity and increase mechanical stability 0 2008
7,708,548 Molds for fabricating stents with profiles for gripping a balloon catheter 1 2008
8,007,529 Medicated porous metal prosthesis 2 2008
8,414,642 Biodegradable stent of a polyorthoester polymer or a polyanhydride polymer 0 2008
8,382,815 modified surface for an implantable device and a method of producing the same 0 2009
8,293,367 Nanoshells on polymers 0 2011
 
ABBOTT CARDIOVASCULAR SYSTEMS INC. (23)
7,964,210 Degradable polymeric implantable medical devices with a continuous phase and discrete phase 0 2006
8,048,448 Nanoshells for drug delivery 0 2006
7,763,198 Method for retaining a vascular stent on a catheter 2 2006
8,017,237 Nanoshells on polymers 0 2006
8,099,849 Optimizing fracture toughness of polymeric stent 0 2006
8,343,530 Polymer-and polymer blend-bioceramic composite implantable medical devices 0 2006
8,262,723 Implantable medical devices fabricated from polymer blends with star-block copolymers 0 2007
8,034,287 Radiation sterilization of medical devices 3 2007
7,951,194 Bioabsorbable stent with radiopaque coating 0 2007
7,829,008 Fabricating a stent from a blow molded tube 2 2007
8,216,209 Method and apparatus for delivering an agent to a kidney 0 2007
7,959,857 Radiation sterilization of medical devices 2 2007
8,293,260 Elastomeric copolymer coatings containing poly (tetramethyl carbonate) for implantable medical devices 0 2007
8,202,528 Implantable medical devices with elastomeric block copolymer coatings 4 2007
8,425,591 Methods of forming polymer-bioceramic composite medical devices with bioceramic particles 0 2007
8,128,688 Carbon coating on an implantable device 0 2007
8,048,441 Nanobead releasing medical devices 0 2007
8,016,879 Drug delivery after biodegradation of the stent scaffolding 1 2007
7,901,452 Method to fabricate a stent having selected morphology to reduce restenosis 8 2007
7,823,263 Method of removing stent islands from a stent 0 2007
7,955,379 Stent and catheter assembly and method for treating bifurcations 1 2007
8,435,550 Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device 0 2008
8,221,112 Method for retaining a vascular stent on a catheter 0 2011
 
MAQUET CARDIOVASCULAR LLC (6)
5,527,353 Implantable tubular prosthesis 79 1993
5,800,510 Implantable tubular prosthesis 17 1995
5,911,753 Implantable tubular prosthesis 12 1997
6,099,557 Implantable tubular prosthesis 17 1999
6,589,468 Method of forming an implantable tubular prosthesis 8 2000
6,814,753 Implantable tubular prosthesis 13 2003
 
THE CLEVELAND CLINIC FOUNDATION (5)
6,579,307 Endovascular prosthesis having a layer of biological tissue 11 2001
7,137,947 Endovascular prosthesis having a layer of biological tissue 0 2003
7,547,322 Prosthetic valve and method for making same 15 2004
7,377,938 Prosthetic cardiac value and method for making same 21 2004
7,559,953 Method for fixing tissue 1 2005
 
AEROQUIP CORPORATION (3)
5,562,727 Intraluminal graft and method for insertion thereof 85 1994
5,554,180 Intraluminal stenting graft 68 1995
5,697,968 Check valve for intraluminal graft 79 1995
 
BOSTON SCIENTIFIC SCIMED, INC. (3)
5,693,085 Stent with collagen 418 1995
5,681,345 Sleeve carrying stent 87 1996
6,391,052 Stent with collagen 126 1997
 
VASCULAR CONCEPTS HOLDINGS LIMITED (3)
6,475,235 Encapsulated stent preform 23 1999
6,746,478 Stent formed from encapsulated stent preforms 5 2002
7,000,305 Method for manufacturing a wire stent coated with a biocompatible fluoropolymer 6 2003
 
RAMUS MEDICAL TECHNOLOGIES (2)
5,865,723 Method and apparatus for forming vascular prostheses 90 1995
6,494,904 Method and apparatus for forming vascular prostheses 25 1998
 
STRYKER NV OPERATIONS LIMITED (2)
6,231,590 Bioactive coating for vaso-occlusive devices 67 1999
8,016,852 Bioactive components for incorporation with vaso-occlusive members 0 2003
 
W. L. GORE & ASSOCIATES, INC. (2)
5,762,600 Blood contact surfaces employing natural subendothelial matrix and methods for making and using the same 29 1996
5,776,182 Blood contact surfaces employing natural subendothelial matrix and method for making and using the same 19 1996
 
BARD PERIPHCRAL VASCULAR, INC. (1)
6,214,039 Covered endoluminal stent and method of assembly 65 1998
 
BARD PERIPHERAL VASCULAR, INC. (1)
6,558,414 Partial encapsulation of stents using strips and bands 32 1999
 
CORLIFE GBR (1)
6,379,963 Process for producing a vascularized bioartificial tissue and an experimental reactor for carrying out the process 1 2001
 
EBARA TECHNOLOGIES, INC. (1)
7,971,333 Manufacturing process for polymetric stents 3 2006
 
EDWARDS LIFESCIENCES CORPORATION (1)
5,976,192 Method of forming an externally supported tape reinforced vascular graft 87 1996
 
ILBAWI; MICHAEL N. (1)
5,326,374 Body-implantable device for controlling the size of a fluid passageway 31 1992
 
IMPRA, INC. (1)
6,004,348 Endoluminal encapsulated stent and methods of manufacture and endoluminal delivery 164 1998
 
RTI BIOLOGICS, INC. (1)
6,290,718 Luminal graft, stent or conduit made of cortical bone 6 1998
 
SOOHO MEDI-TECH CO., LTD. (1)
5,545,211 Stent for expanding a lumen 161 1994
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (3)
5,330,500 Self-expanding endovascular stent with silicone coating 477 1992
5,645,581 Vascular prosthesis 9 1994
5,755,659 Method of making a vascular prosthesis 4 1997