Malaria-specific DNA sequences, expression products thereof, and the use thereof
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United States of America Patent
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Mar 16, 1993
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app pub date -
Jun 27, 1991
filing date -
Dec 30, 1987
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Abstract
The invention relates to malaria-specific DNA sequences, to the expression products thereof, and to the use thereof. A combination of three of the expression proteins whose DNA sequences were isolated by screening a lambda gt11 gene bank with a monospecific antiserum against the protective 41kD antigen bend from P. falciparum protects Aotus monkeys completely from a P. falciparum infection in model experiments.
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