Compounds active as inhibitors of the cholesterol biosynthesis
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United States of America Patent
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Mar 23, 1993
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app pub date -
May 4, 1990
filing date -
Jul 29, 1988
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Expired
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Abstract
The compounds of formula ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3, and R.sub.4 have the meanings given in the specification, as described. The compounds of formula I are active as inhibitors of the enzyme HMG-CoA reductase and can be used in therapy as anti-hypercholesterolemics.
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