Synthetic bioadhesive
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United States of America Patent
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Mar 30, 1993
Grant Date -
N/A
app pub date -
Dec 14, 1990
filing date -
Dec 14, 1990
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
This invention pertains to a synthetic adhesive composition for use in aqueous environments. The composition comprises polypeptide chains having an .alpha.-helical structure in aqueous environments and capable of cohesive and adhesive interactions. The polypeptide chains comprise polar and apolar amino acids, the apolar and polar amino acids being arranged to define apolar and polar vertical spiraling stripes on the helix surface. The apolar stripes allow the polypeptide chains to aggregate into superhelical structures and the polar stripes allow interchain crosslinking within and between the superhelical structures.
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