US Patent No: 5,197,977

Number of patents in Portfolio can not be more than 2000

Drug delivery collagen-impregnated synthetic vascular graft

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Abstract

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A collagen impregnated vascular graft including drug materials complexed with the collagen to be released slowly from the graft following implant. The graft is a porous synthetic vascular graft substrate having collagen fixed to the graft substrate and cross-linking the collagen in situ to render the porous substrate blood-tight. The drug materials complexed with the collagen fibrils may include antithrombic agents, antibacterial, antimicrobial agents, antifungal agents and the like.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
BOSTON SCIENTIFIC SCIMED, INC.MAPLE GROVE, MN4975

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chvapil, Milos Tucson, AZ 15 1048
Hoffman, Jr Harmon Wyckoff, NJ 3 698
Schankereli, Kemal Stillwater, MN 40 2474

Cited Art Landscape

Patent Info (Count) # Cites Year
 
MEADOX MEDICALS, INC. (1)
4,842,575 Method for forming impregnated synthetic vascular grafts 131 1988
 
Other [Check patent profile for assignment information] (1)
4,416,028 Blood vessel prosthesis 105 1981

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
ADVANCED CARDIOVASCULAR SYSTEMS, INC. (125)
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7,435,255 Drug-eluting stent and methods of making 4 2003
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7,761,968 Method of crimping a polymeric stent 10 2006
7,959,940 Polymer-bioceramic composite implantable medical devices 3 2006
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7,951,194 Bioabsorbable stent with radiopaque coating 2 2007
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7,959,857 Radiation sterilization of medical devices 6 2007
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8,202,528 Implantable medical devices with elastomeric block copolymer coatings 4 2007
8,425,591 Methods of forming polymer-bioceramic composite medical devices with bioceramic particles 0 2007
8,535,372 Bioabsorbable stent with prohealing layer 0 2007
8,128,688 Carbon coating on an implantable device 0 2007
8,048,441 Nanobead releasing medical devices 1 2007
8,016,879 Drug delivery after biodegradation of the stent scaffolding 4 2007
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The Trustees of Columbia University in the City of New York (12)
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The United States of America as represented by the Secretary of the Army (1)
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UNIVERSITY OF LEICESTER (1)
6,774,278 Coated implantable medical device 229 1998
 
UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (1)
5,578,073 Thromboresistant surface treatment for biomaterials 362 1994
 
VASCUTEK LIMITED (1)
6,976,952 Expanded polytetrafluoroethylene vascular graft with coating 6 2000
 
WARSAW ORTHOPEDIC, INC. (1)
7,923,250 Methods of expressing LIM mineralization protein in non-osseous cells 0 2002
 
WHD ELECTRONISCHE PRUEFTECHNIK (1)
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WILLIAM A. COOK AUSTRALIA PTY. LTD. (1)
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ZIMMER ORTHOBIOLOGICS, INC. (1)
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Other [Check patent profile for assignment information] (3)
6,616,699 Foam-type vascular prosthesis with well-defined angio-permissive open porosity 4 2001
6,645,241 Endoprosthesis that can be percutaneously implanted in the patient's body 26 2001
6,521,750 Bone mineralization proteins, DNA, vectors, expression systems 15 2001