US Patent No: 5,197,977

Number of patents in Portfolio can not be more than 2000

Drug delivery collagen-impregnated synthetic vascular graft

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Abstract

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A collagen impregnated vascular graft including drug materials complexed with the collagen to be released slowly from the graft following implant. The graft is a porous synthetic vascular graft substrate having collagen fixed to the graft substrate and cross-linking the collagen in situ to render the porous substrate blood-tight. The drug materials complexed with the collagen fibrils may include antithrombic agents, antibacterial, antimicrobial agents, antifungal agents and the like.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
BOSTON SCIENTIFIC SCIMED, INC.MAPLE GROVE, MN4560

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chvapil, Milos Tucson, AZ 15 1088
Hoffman, Jr Harmon Wyckoff, NJ 3 712
Schankereli, Kemal Stillwater, MN 40 2729

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
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MEADOX MEDICALS, INC. (1)
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* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
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8,048,448 Nanoshells for drug delivery 1 2006
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ASCEND PERFORMANCE MATERIALS LLC (1)
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ADVANCED CARDIOVASCULAR SYSTEMS, INC. (125)
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7,144,422 Drug-eluting stent and methods of making the same 21 2002
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7,163,715 Spray processing of porous medical devices 94 2002
7,105,018 Drug-eluting stent cover and method of use 75 2002
7,470,283 Biodegradable drug delivery material for stent 9 2003
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6,955,688 Stent and catheter assembly and method for treating bifurcations 70 2003
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7,875,283 Biodegradable polymers for use with implantable medical devices 8 2005
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7,658,880 Polymeric stent polishing method and apparatus 4 2005
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7,476,245 Polymeric stent patterns 8 2005
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7,241,309 Self-aggregating protein compositions and use as sealants 0 2001
7,585,319 Self-aggregating protein compositions and use as sealants 0 2004
8,388,679 Single continuous piece prosthetic tubular aortic conduit and method for manufacturing the same 0 2010
8,696,741 Woven prosthesis and method for manufacturing the same 0 2010
 
ICON MEDICAL CORP. (6)
7,211,108 Vascular grafts with amphiphilic block copolymer coatings 10 2004
8,740,973 Polymer biodegradable medical device 0 2006
7,488,444 Metal alloys for medical devices 7 2006
8,323,333 Fragile structure protective coating 0 2006
8,100,963 Biodegradable device 2 2006
8,808,618 Process for forming an improved metal alloy stent 1 2009
 
BOSTON SCIENTIFIC SCIMED, INC. (7)
* 6,129,757 Implantable members for receiving therapeutically useful compositions 26 1998
6,210,436 Implantable members for receiving therapeutically useful compositions 26 1999
6,447,542 Implantable members for receiving therapeutically useful compositions 183 2000
8,067,022 Therapeutic inhibitor of vascular smooth muscle cells 0 2001
* 6,656,162 Implantable drug delivery stents 212 2002
8,158,670 Therapeutic inhibitor of vascular smooth muscle cells 0 2007
8,097,642 Therapeutic inhibitor of vascular smooth muscle cells 0 2007
 
LIFESHIELD SCIENCES LLC (7)
* 5,665,114 Tubular expanded polytetrafluoroethylene implantable prostheses 115 1994
* 5,693,085 Stent with collagen 522 1995
* 5,716,660 Tubular polytetrafluoroethylene implantable prostheses 27 1995
6,391,052 Stent with collagen 175 1997
6,521,284 Process for impregnating a porous material with a cross-linkable composition 82 1999
* 6,827,737 EPTFE covering for endovascular prostheses and method of manufacture 72 2001
8,118,864 Drug delivery endovascular graft 1 2004
 
EBARA TECHNOLOGIES, INC. (1)
7,971,333 Manufacturing process for polymetric stents 47 2006
 
ICON INTERVENTIONAL SYSTEMS, INC. (5)
8,603,158 Irradiated stent coating 0 2004
8,016,881 Sutures and surgical staples for anastamoses, wound closures, and surgical closures 5 2004
8,070,796 Thrombosis inhibiting graft 2 2005
7,967,855 Coated medical device 4 2005
8,114,152 Stent coating 7 2008
* Cited By Examiner