Processes of converting taxanes into baccatin III
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United States of America Patent
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Apr 13, 1993
Grant Date -
N/A
app pub date -
Aug 14, 1992
filing date -
Aug 14, 1992
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to a process of converting partially purified taxane mixtures into Baccatin III. The process for the preparation of Baccatin III includes contacting a mixture containing at least one taxane compound having an ester linkage at the C-13 position with at least one borohydride reducing salt in a reaction solvent in the present of a Lewis acid.
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