Transmucosal formulations of low molecular weight peptide drugs
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United States of America Patent
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Apr 20, 1993
Grant Date -
N/A
app pub date -
Apr 9, 1990
filing date -
Oct 10, 1987
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A drug delivery composition comprising a plurality of microspheres and active drug associated with each microsphere, the drug being for systemic delivery and having a maximum molecular weight of 6000, and the composition being substantially free of an enhancer. The microspheres may be of starch, gelatin or albumin. Suitable drugs include peptides, such as insulin, and antigenic vaccine ingredients. The compositions are suitable for delivery across a mucosal surface such as the vagina, eye or nose.
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