Penetration enhancers for transdermal delivery of systemic agents
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United States of America Patent
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Apr 20, 1993
Issued Date -
N/A
app pub date -
Aug 6, 1990
filing date -
Jan 31, 1986
priority date (Note) -
Expired
status (Latency Note)
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Abstract
This invention relates to a method for administering systemically active agents including therapeutic agents through the skin or mucosal membranes of humans and animals in a transdermal device or formulation comprising topically administering with said systemic agent an effective amount of a membrane penetration enhancer having the structural formula ##STR1## wherein X is selected from the group consisting of oxygen and sulfur; R' is H or a lower alkyl group having 1-4 carbon atoms; m is 2-6; n is 0-17 and R is --CH.sub.3 ; wherein R is H or a lower alkyl group, m is 5-7 and n is 0-17.
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