Determination of glycated (glycosylated) hemoglobin in blood
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United States of America Patent
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Apr 27, 1993
Issued Date -
N/A
app pub date -
Oct 30, 1990
filing date -
Mar 29, 1985
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The concentration of glycated hemoglobin, HbA.sub.1c, in hemoglobin from diabetic patients is regarded as a useful means of assessing the adequacy of diabetes control. This invention comprises a monoclonal antibody which, due to its specific binding of HbA.sub.1c, can be used for the determination of HbA.sub.1c in the absence of prior denaturation, in blood samples by such analytical methods as radioimmuno assay or enzyme-linked immunosorbent assay. The invention also comprises hybridoma cell lines which produce monoclonal antibodies of the invention.
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