N-(.omega., (.omega.-1)-dialkyloxy)- and N-(.omega., (.omega.-1)-dialkenyloxy)-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor

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United States of America Patent

PATENT NO 5208036
SERIAL NO

07614412

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention relates to compounds of the formula ##STR1## or an optical isomer thereof wherein R.sup.1 and R.sup.2 are the same or different and are an alkyl or alkenyl group of 6 to 24 carbon atoms; R.sup.3, R.sup.4 and R.sup.5 are the same or different and are alkyl of 1 to 8 carbon atoms, aryl, aralkyl of 7 to 11 carbon atoms, or when two or three of R.sup.3, R.sup.4, and R.sup.5 are taken together to form quinuclidino, piperidino, pyrrolidino, or morpholino; n is 1 to 8; and X is a pharmaceutically acceptable anion.

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Patent Owner(s)

  • SYNTEX (U.S.A.) INC.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Eppstein, Deborah A Menlo Park, CA 18 3947
Felgner, Philip L Los Altos, CA 49 5868
Gadek, Thomas R Oakland, CA 35 1558
Jones, Gordon H Cupertino, CA 25 1515
Roman, Richard B Fairhope, AL 9 1336

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