Methods for providing localized therapeutic heat to biological tissues and fluids using gas filled liposomes
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United States of America Patent
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May 11, 1993
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N/A
app pub date -
Jun 18, 1991
filing date -
Dec 22, 1989
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Abstract
Gas filled liposomes prepared by a vacuum drying gas instillation method and/or gas filled liposomes substantially devoid of liquid in the interior thereof, are presented as novel potentiators for ultrasonic hyperthermia. The liposomes of the present invention, which may be administered into the vasculature, interstitially or into any body cavity are designed to accumulate in cancerous and diseased tissues. When therapeutic ultrasonic energy is applied to the diseased region heating is increased because of the greater effectiveness of sound energy absorption caused by these agents.
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