Oligonucleotide analogs containing sulfur linkages
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United States of America Patent
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Jun 1, 1993
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N/A
app pub date -
Jun 6, 1988
filing date -
Jun 6, 1988
priority date (Note) -
Expired
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Abstract
Analogs of DNA containing sulfides, sulfoxides, and sulfones as linking groups between subunits capable of forming bonds with natural oligonucleotides are described. The analogs are lipophilic, stable to chemical degradation under a wide range of conditions and stable to enzymatic degradation in vivo.
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