Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders
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United States of America Patent
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Jun 8, 1993
Issued Date -
N/A
app pub date -
Sep 17, 1990
filing date -
Oct 4, 1989
priority date (Note) -
Expired
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Abstract
This invention relates to the use of tocotrienol, gamma-tocotrienol and delta-tocotrienol in reducing hypercholesterolemia, hyperlipidemia and thromboembolic disorders in mammals. [The isolation of these tocotrienols from natural sources and their chemical synthesis is disclosed.] The chemical synthesis of these tocotrienols is disclosed. The present invention also relates to prodrugs and pharmaceutical compositions of gamma-tocotrienol, delta-tocotrienol and tocotrienol and uses thereof.
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