Recombinant DNA encoding PDGF A-chain polypeptide and expression vectors

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United States of America Patent

PATENT NO 5219759
SERIAL NO

07574540

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Abstract

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DNA encoding two forms of PDGF A-chain polypeptide, the construction of expression vectors for expressing such DNA in yeast and mammalian cells, and the expression of such DNA in yeast and mammalian cells to produce active PDGF A-chain homodimer and active PDGF A-chain/B-chain heterodimer are disclosed.

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Patent Owner(s)

Patent OwnerAddress
CHIRON CORPORATION4650 HORTON STREET EMERYVILLE CALIFORNIA 94608 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bell, Graeme I San Francisco, CA 19 411
Betsholtz, Christer Uppsala, SE 7 87
Heldin, Carl-Henrik Uppsala, SE 49 444
Knott, Timothy J London, GB2 7 43
Scott, James London, GB2 90 1444
Westermark, Bengt Uppsala, SE 7 129

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