Deacetylcolchicine derivatives
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United States of America Patent
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Jun 15, 1993
Grant Date -
N/A
app pub date -
Dec 20, 1991
filing date -
Dec 25, 1990
priority date (Note) -
Expired
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Abstract
Deacetylcolchicine derivatives represented by the formula ##STR1## wherein R denotes a residue obtained by removing COOH from a C.sub.3 -C.sub.7 sugar carboxylic acid, and a hydroxyl group present in the residue may properly be protected with a protecting group of the hydroxyl group. Said deacetylcolchicine derivatives have less toxicity and strong effect for inhibiting proliferation of tumor cells, and are expected to be used as an antitumor agent.
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