Ethynylcyclohexene compounds and processes for manufacture thereof

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United States of America Patent

PATENT NO 5227507
SERIAL NO

07498061

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Abstract

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A process for the manufacture of compounds of the general formula ##STR1## wherein R.sup.1 signifies hydroxy or an etherified hydroxy group, and of zeaxanthin by converting a compound of the general formula ##STR2## wherein R.sup.1 has the above significance, in an inert organic solvent into the acetylenide and reacting this with methyl vinyl ketone, reducing the alcoholate obtained or the alcohol (obtained after hydrolysis of the alcoholate) of the general formula ##STR3## wherein R.sup.1 has the above significance, in an inert organic solvent with an aluminum hydride of the general formula R.sub.x MAlH.sub.4-x III wherein M signifies alkali metal, R represents C.sub.1 -C.sub.10 -alkoxy or a group of the formula C.sub.n H.sub.2n+1 --O--C.sub.m H.sub.2m --O--, m and n each individually denote whole numbers of 1 to 7 and x stands for 0, 1, 2 or 3, and subsequently hydrolyzing to give the compound of formula IV and, if desired, converting the compound of formula IV obtained into zeaxanthin.

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Patent Owner(s)

Patent OwnerAddress
ROCHE VITAMINS INC45 EISENHOWER DRIVE PARAMUS NJ 07652

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lukac, Teodor Aesch, CH 13 152
Soukup, Milan Passaic, NJ 23 74

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