Antibodies to A4 amyloid peptide
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United States of America Patent
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Jul 27, 1993
Issued Date -
N/A
app pub date -
Jul 22, 1991
filing date -
Oct 8, 1987
priority date (Note) -
Expired
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Abstract
Monoclonal antibodies to a 28-mer peptide present within A4-amyloid are described. These antibodies exhibit unexpected specificity for amyloid plaque structures previously unrecognized in Alzheimer's disease brains. These monoclonal antibodies are useful as reagents for use in assays and imaging of A4-amyloid in Alzheimer's disease patients.
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