Liquid dispenser

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 5232664
SERIAL NO

07762327

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A dispenser which can deliver precise small amounts of a liquid is disclosed. The dispenser is particularly suited to applying reagents in a biological test such as an immunoassay. It includes a reservoir chamber linked to a dispense chamber via a check valve, the two chambers preferably being in the form of syringes. An outlet line leading from the dispense chamber to a nozzle includes a delay check valve (preferably a ball inside a cylindrical chamber) which allows continuous outward flow, but shuts off flow in the reverse direction after allowing a predetermined volume to pass. The process of refilling the dispense chamber from the reservoir chamber creates reverse flow in the nozzle and causes a hanging drop of liquid at the tip of the nozzle to be withdrawn.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
VENTANA MEDICAL SYSTEMS, INC.TUCSON, AZ188

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
DeGroff, Michael J Tucson, AZ 4 317
Krawzak, Thomas P Leominster, MA 1 127
McGraw, Brian J Tucson, AZ 2 145
Nunnery, David W Tucson, AZ 4 208

Cited Art Landscape

Patent Info (Count) # Cites Year
 
American Monitor Corporation (1)
* 4818706 Reagent-dispensing system and method 25 1984
 
Other [Check patent profile for assignment information] (1)
* 4601212 Precision micropipettor 4 1985
 
Baker Instruments Corp. (1)
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TOYO SODA MANUFACTURING COMPANY LIMITED, 4560, OOZA TONDA SHINNANYO-SHI YAMAGUCHI, JAPAN (1)
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ROCHE DIAGNOSTICS OPERATIONS, INC. (1)
* 4868129 Apparatus and method for dilution and mixing of liquid samples 186 1987
 
Labsystems Oy (1)
* 4690005 Diluting dosage device 15 1985
 
Jencons (Scientific) Limited (1)
* 4760939 Liquid dosing device with digital display 27 1986
 
KABUSHIKI KAISHA TOSHIBA (1)
* 4844868 Automatic chemical analysis reagent distribution and analysis apparatus 116 1986
 
Glasgeratebau Hirschmann (1)
* 4526294 Dispenser for dispensing liquids in controlled quantities from a bottle 100 1983
 
Japan Spectroscopic Co., Ltd. (1)
* 4429583 Liquid uptake and discharge apparatus 26 1982
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (29)
6534008 In situ heat induced antigen recovery and staining apparatus and method 88 2000
* 2002/0059,945 Sample wash station assembly 6 2002
7250301 In situ heat induced antigen recovery and staining method 30 2002
6855292 In situ heat induced antigen recovery and staining apparatus and method 50 2003
7632461 In situ heat induced antigen recovery and staining apparatus and method 24 2004
7622077 In situ heat induced antigen recovery and staining apparatus and method 24 2004
7476362 In situ heat induced antigen recovery and staining apparatus and method 65 2004
* 2007/0231,889 In situ heat induced antigen recovery and staining method 13 2007
8007720 In situ heat induced antigen recovery and staining apparatus and method 22 2008
8052927 In situ heat induced antigen recovery and staining method 22 2009
8486335 In situ heat induced antigen recovery and staining apparatus and method 2 2009
8377377 In situ heat induced antigen recovery and staining apparatus and method 4 2009
* 2010/0028,978 IN SITU HEAT INDUCED ANTIGEN RECOVERY AND STAINING APPARATUS AND METHOD 11 2009
8007721 In Situ heat induced antigen recovery and staining apparatus and method 22 2009
8092742 In situ heat induced antigen recovery and staining apparatus and method 22 2009
8071023 In situ heat induced antigen recovery and staining apparatus and method 22 2009
* 2011/0150,725 IN SITU HEAT INDUCED ANTIGEN RECOVERY AND STAINING APPARATUS AND METHOD 2 2011
8329100 In situ heat induced antigen recovery and staining apparatus and method 5 2011
8313694 In situ heat induced antigen recovery and staining apparatus and method 5 2011
8574494 In situ heat induced antigen recovery and staining method 3 2011
8354058 In situ heat induced antigen recovery and staining apparatus and method 5 2011
8696988 In situ heat induced antigen recovery and staining apparatus and method 3 2013
9267868 In Situ heat induced antigen recovery and staining apparatus and method 1 2013
9176033 In situ heat induced antigen recovery and staining method 3 2013
9464974 In situ heat induced antigen recovery and staining apparatus and method 2 2014
* 2015/0158,042 Liquid Dispenser That Can Be Worn As Jewelry 0 2014
9772266 In situ heat induced antigen recovery and staining method 0 2015
9606034 In situ heat induced antigen recovery and staining method 0 2015
9766165 In situ heat induced antigen recovery and staining apparatus and method 0 2016
 
SEIKO EPSON CORPORATION (1)
* 2004/0131,505 Dispenser, dispenser array, manufacturing method for dispenser, inspection device, inspection method and biochip 21 2003
 
The Board of Regents of the University of Oklahoma (2)
7842387 Methods for growing and harvesting carbon nanotubes 7 2006
* 2007/0092,431 Methods for growing and harvesting carbon nanotubes 57 2006
 
MILLIPORE CORPORATION (1)
* 2009/0104,688 Microbiological analysis machine 0 2008
 
WABTEC HOLDING CORP. (1)
6422431 Microvolume liquid handling system 23 2001
 
Cell Marque Corporation (1)
6489171 Chemical dispensing system and method 53 1997
 
Biocare, LLC (1)
8501434 Method for processing non-liquid biological samples with dynamic application of a processing liquid 1 2012
 
JUNIOR INSTRUMENTS (FRENCH CORPORATION) (1)
* 2004/0028,565 Automatic pipetting device with rinsing 5 2003
 
HITACHI, LTD. (3)
* 6599477 Chemical analysis apparatus 6 1998
* 6193933 Automatic analysis apparatus 44 1998
* 6197255 Chemical analyzing apparatus 16 1999
 
BIOCARE MEDICAL, LLC (1)
9442049 Efficient processing systems and methods for biological samples 2 2013
 
VENTANA MEDICAL SYSTEMS, INC. (32)
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* 5654200 Automated slide processing apparatus with fluid injector 165 1995
* 5650327 Method for mixing reagent and sample mounted on a slide 158 1995
* 6093574 Method and apparatus for rinsing a microscope slide 125 1997
* 6045759 Fluid dispenser 78 1997
* 6352861 Automated biological reaction apparatus 159 1999
6416713 Fluid dispenser 45 2000
6192945 Fluid dispenser 61 2000
8609023 Memory management method and apparatus for automated biological reaction system 3 2000
6945128 Fluid dispenser 18 2001
* 2002/0034,456 Fluid dispenser 7 2001
7118918 Automated biological reaction method 17 2001
6943029 Automated biological reaction apparatus 123 2002
* 2002/0110,494 Method and apparatus for modifying pressure within a fluid dispenser 33 2002
6827901 Automated biological reaction apparatus 93 2002
7270785 Automated molecular pathology apparatus having fixed slide platforms 33 2002
7303725 Automated high volume slide staining system 55 2003
7378055 Automated molecular pathology apparatus having fixed slide platforms 50 2003
7378058 Method and apparatus for modifying pressure within a fluid dispenser 21 2003
* 2004/0197,230 Method and apparatus for modifying pressure within a fluid dispenser 11 2003
* 2005/0135,972 Method and apparatus for modifying pressure within a fluid dispenser 25 2004
7470541 Automated biological reaction apparatus 20 2004
7468161 Automated high volume slide processing system 35 2005
8663991 Automated high volume slide processing system 1 2005
8137619 Memory management method and apparatus for automated biological reaction system 8 2005
* 2006/0190,185 Memory management method and apparatus for automated biological reaction system 35 2005
7404927 Automated molecular pathology apparatus having fixed slide platforms 31 2005
8048373 Automated high volume slide staining system 4 2007
8147773 Method and apparatus for modifying pressure within a fluid dispenser 2 2011
* 2011/0168,744 METHOD AND APPARATUS FOR MODIFYING PRESSURE WITHIN A FLUID DISPENSER 0 2011
8790596 Dispenser with filter device 0 2012
9528918 Automated high volume slide processing system 0 2013
 
Hallmont LLC (2)
7461761 Harness for suspending detergent container 5 2005
* 2005/0161,473 Harness for suspending detergent container 1 2005
 
CLINICAL DATA, INC. (1)
* 2006/0096,860 Analyte recognition system 0 2004
 
ONTOGEN CORPORATION (1)
* 6416718 Sample wash station assembly 35 1999
 
Drummond Scientific Company (1)
7396512 Automatic precision non-contact open-loop fluid dispensing 11 2003
 
ABBOTT LABORATORIES (2)
5856194 Method for determination of item of interest in a sample 52 1996
5795784 Method of performing a process for determining an item of interest in a sample 103 1996
 
MATRIX TECHNOLOGIES LLC (2)
* 9696332 Automated liquid handling device 0 2011
* 2012/0100,047 AUTOMATED LIQUID HANDLING DEVICE 1 2011
 
PACKARD INSTRUMENT COMPANY, INC. (8)
* 6083762 Microvolume liquid handling system 68 1998
* 6079283 Method for aspirating sample liquid into a dispenser tip and thereafter ejecting droplets therethrough 43 1998
6203759 Microvolume liquid handling system 76 1998
* 5927547 System for dispensing microvolume quantities of liquids 169 1998
* 6112605 Method for dispensing and determining a microvolume of sample liquid 27 1999
6521187 Dispensing liquid drops onto porous brittle substrates 31 2000
6537817 Piezoelectric-drop-on-demand technology 15 2000
6592825 Microvolume liquid handling system 59 2001
 
BIOLYPH, LLC (4)
8940539 Reagent preparation and dispensing device and methods for the same 0 2009
* 2011/0127,294 REAGENT PREPARATION AND DISPENSING DEVICE AND METHODS FOR THE SAME 6 2009
8919390 Reagent preparation and dispensing device 1 2010
8973749 Reagent preparation assembly 0 2011
 
DAKOCYTOMATION DENMARK A/S (1)
7758809 Method and system for pretreatment of tissue slides 2 2009
 
HONEYWELL INTERNATIONAL INC. (1)
8003056 Gas analyzer apparatus and method of analyzing gases 0 2007
 
DAKO DENMARK A/S (30)
* 5645114 Dispensing assembly with interchangeable cartridge pumps 135 1994
* 5947167 Dispensing assembly with interchangeable cartridge pumps 113 1997
* 6092695 Interchangeable liquid dispensing cartridge pump 103 1998
6180061 Moving platform slide stainer with heating elements 103 1998
6244474 Interchangeable liquid dispensing cartridge pump 36 2000
7718435 Automated slide stainer with slide housing 11 2000
7648678 Method and system for pretreatment of tissue slides 12 2003
8257968 Method and apparatus for automatic staining of tissue samples 7 2003
8216512 Apparatus for automated processing biological samples 1 2003
7960178 Enhanced scheduling sample processing system and methods of biological slide processing 10 2003
7400983 Information notification sample processing system and methods of biological slide processing 58 2003
9778273 Isolated communication sample processing system and methods of biological slide processing 0 2003
8298815 Systems and methods of sample processing and temperature control 6 2003
* 2004/0191,128 Slide stainer with heating 31 2004
7217392 Random access slide stainer with independent slide heating regulation 24 2004
* 2006/0147,351 Diaphram metering chamber dispensing systems 11 2004
* 2004/0241,050 Random access slide stainer with independent slide heating regulation 0 2004
7553672 Random access slide stainer with independent slide heating regulation 15 2007
* 2007/0281,364 Random access slide stainer with independent slide heating regulation 2 2007
7937228 Information notification sample processing system and methods of biological slide processing 10 2008
8386195 Information notification sample processing system and methods of biological slide processing 8 2011
8394635 Enhanced scheduling sample processing system and methods of biological slide processing 10 2011
8529836 Apparatus for automated processing biological samples 4 2012
8663978 Method and apparatus for automatic staining of tissue samples 3 2012
8788217 Information notification sample processing system and methods of biological slide processing 2 2013
8673642 Enhanced scheduling sample processing system and methods of biological slide processing 4 2013
8784735 Apparatus for automated processing biological samples 0 2013
9599630 Method and apparatus for automatic staining of tissue samples 0 2014
8969086 Enhanced scheduling sample processing system and methods of biological slide processing 1 2014
9229016 Information notification sample processing system and methods of biological slide processing 0 2014
 
SHIMADZU CORPORATION (2)
* 7931789 Device for charging separation buffer liquid to microchip, and microchip processing device equipped with the charging device, electrophoresis method in capillary channel and its microchip processing device 0 2006
* 2007/0175,757 Device for charging separation buffer liquid to microchip, and microchip processing device equipped with the charging device, electrophoresis method in capillary channel and its microchip processing device 3 2006
 
EMD MILLIPORE CORPORATION (3)
8071022 Decontamination method and system implementing it 1 2008
8815173 Decontamination method and system implementing it 0 2011
* 2011/0206,559 Decontamination Method And System Implementing It 0 2011
 
ABBOTT LABORATORIES (1)
6562298 Structure for determination of item of interest in a sample 11 1999
 
SAKURA FINETEK U.S.A., INC. (11)
7501283 Fluid dispensing apparatus 13 2003
* 2005/0035,156 Fluid dispensing apparatus 16 2003
7767152 Reagent container and slide reaction retaining tray, and method of operation 4 2006
7744817 Manifold assembly 57 2006
9518899 Automated reagent dispensing system and method of operation 0 2006
8459509 Fluid dispensing apparatus 0 2006
8752732 Fluid dispensing system 0 2011
8932543 Automated staining system and reaction chamber 1 2011
8580568 Traceability for automated staining system 0 2011
9005980 Traceability for automated staining system 0 2013
9016526 Fluid dispensing system 0 2014
 
PWRISTINE, INC. (3)
* 2008/0251,539 Wristband-Mounted Dispenser for Liquids or Powders 1 2006
* 2010/0025,432 WRISTBAND-MOUNTED DISPENSER FOR LIQUIDS AND POWDERS WITH AN IMPROVED DISPENSING MECHANISM 2 2008
* 2009/0014,475 WRISTBAND-MOUNTED DISPENSER FOR LIQUIDS AND POWDERS WITH AN IMPROVED DISPENSING MECHANISM 2 2008
 
Angros, Lee H. (6)
8298485 In situ heat induced antigen recovery and staining apparatus and method 0 2006
7951612 In situ heat induced antigen recovery and staining apparatus and method 11 2006
* 2006/0281,116 In situ heat induced antigen recovery and staining apparatus and method 13 2006
* 2006/0275,861 In situ heat induced antigen recovery and staining apparatus and method 37 2006
8361388 In situ heat induced antigen recovery and staining apparatus and method 3 2011
8541244 In situ heat induced antigen recovery and staining apparatus and method 1 2011
 
NCH CORPORATION (5)
* 8961893 Automated chemical diluter system having disposable components 1 2009
* 2011/0008,220 Automated Chemical Diluter System Having Disposable Components 6 2009
8551762 System and apparatus for feeding, solubilizing, growing and discharging a biological material 1 2009
* 2011/0081,713 System and Apparatus for Feeding, Solubilizing, Growing and Discharging a Biological Material 4 2009
9495508 System and apparatus for feeding, solubilizing, growing and discharging a biological material 0 2013
 
ANGROS, LEE (4)
7897106 Situ heat induced antigen recovery and staining apparatus and method 19 2006
* 2006/0275,889 In situ heat induced antigen recovery and staining apparatus and method 18 2006
9354145 In situ heat induced antigen recovery and staining apparatus and method 1 2013
9719895 In situ heat induced antigen recovery and staining apparatus and method 0 2016
 
CERES INTELLECTUAL PROPERTY COMPANY LIMITED (1)
* 2008/0318,129 Fuel Cell Cathodes 0 2006
* Cited By Examiner