Morphinane-skeletoned hydrazone derivatives
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United States of America Patent
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Aug 3, 1993
Issued Date -
N/A
app pub date -
Oct 6, 1992
filing date -
Apr 22, 1986
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to novel morphinane-skeletoned compounds of the formula (I) ##STR1## wherein Y in-NH phenyl or --NH dintro phenyl, Z is --CH.sub.2 -- CH.sub.2, R.sub.2 is hydroxyl and R.sub.3 is H or methyl, the steric isomers and the pharmaceutically acceptable salts thereof, a novel process for producing the same and pharmaceutical compositions comprising the same as active ingredients. The novel compounds can be used in the therapy as analgetic or morphine-antagonistic agents.
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