Importance

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Abstract

The invention relates to new phenylethanolamines of general formula ##STR1## wherein A represents a straight-chained or branched alkylene group, B represents a bond, an alkylene group, a carbonyl or hydroxymethylene group, R.sub.1 represents a hydrogen atom, a halogen atom or a trifluoromethyl group, R.sub.2 represents a hydrogen atom or an amino group, R.sub.3 represents a cyano group, a hydrogen, chlorine or bromine atom and R.sub.4 represents a hydrogen or halogen atom, an alkyl, hydroxy, alkoxy, carboxy, alkoxycarbonyl, aminocarbonyl, alkylaminocarbonyl or dialkylaminocarbonyl group or an alkoxy group substituted in the end position by a carboxy, alkoxycarbonyl, aminocarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, hydroxy, alkoxy, amino, alkylamino, dialkylamino, pyrrolidino, piperidino or hexamethyleneimino group, the optical isomers and diastereoisomers and acid addition salts thereof. The new compounds of formula I, the optical isomers and diastereoisomers and acid addition salts thereof, particularly the physiologically acceptable acid addition salts thereof with inorganic or organic acids, have valuable pharmacological properties, namely an effect on the metabolism, preferably the effect of lowering blood sugar and reducing body fat and they may also be used as performance enhancers in animals. The new compounds of general formula I above may be prepared by methods known per se.

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First Claim