Process for the purification of hemin, a novel derivative and process for its preparation
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United States of America Patent
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Aug 3, 1993
Grant Date -
N/A
app pub date -
Oct 17, 1991
filing date -
Apr 26, 1989
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Abstract
Process for the purification of hemin by dissolving raw hemin into 1,3-dimethyl-2-imidazolidinone (DMI), the mixture is allowed to cool in order to crystallize the hemin in the form of a 1:3-adduct of hemin and DMI, whereafter the adduct obtained is split by mixing the same with warm water, a lower alcohol or in a mixture thereof, or by heating in a vacuum, and the liberated hemin is recovered. The invention also concerns a novel hemin derivative, that is the 1:3-adduct of hemin and DMI, and a process for its preparation.
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