Therapeutic agents
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United States of America Patent
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Aug 31, 1993
Issued Date -
N/A
app pub date -
Mar 24, 1992
filing date -
Jul 17, 1987
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A high content of 2-(4-isobutylphenyl)propionic acid is achieved in a pharmaceutical composition by solidifying molten 2-(4-isobutylphenyl)propionic acid to provide a unit dose composition. The composition may be prepared by heating the 2-(4-isobutylphenyl)-propionic acid until molten, optionally mixing with pharmaceutically acceptable excipients, forming into a unit dosage presentation and allowing the composition to solidify. Preferably the composition contains greater than 80% ibuprofen or S(+)-ibuprofen and is filled into a hard gelatin capsule.
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