Defensin peptide compositions and methods for their use
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United States of America Patent
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Sep 7, 1993
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N/A
app pub date -
Sep 6, 1989
filing date -
Sep 6, 1989
priority date (Note) -
Expired
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Abstract
A method for treating cutaneous and corneal wounds as well as certain microbial-related diseases comprises topically applying a defensin peptide to the affected tissue. The compositions comprise a natural, synthetic, or analog defensin molecule having both a mitogenic activity capable of stimulating cell growth and an antimicrobial activity capable of inhibiting the growth of a wide variety of pathogens. In addition to therapeutic use, the defensins are useful as mitogens in cell and tissue culture media.
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