Device for determining the concentration of at least one substance in organic tissue
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United States of America Patent
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Sep 14, 1993
Grant Date -
N/A
app pub date -
Jul 18, 1991
filing date -
Jul 19, 1990
priority date (Note) -
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Abstract
A device for determining the concentration of at least one substance in organic tissue includes a subcutaneous needle for insertion into the tissue and a pumping and suction unit which is controlled by a microprocessor and is used for delivering a perfusion fluid and draining it after its partial equilibration with the tissue. The device further includes a sensing unit connected to the microprocessor for determining the concentration of the substance to be analyzed and one or more marker variables. The perfusion fluid, a calibrating solution and at least one drug are provided in replaceable metering ampoules sealed with membranes, whose metering plungers can be actuated by a drive unit controlled by the microprocessor. The metering ampoules communicate with a master capillary leading from the pumping and suction unit to the subcutaneous needle; communication is established via capillary tubes piercing the membranes.
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