Microbial process for production of eicosapentaenoic acid
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United States of America Patent
Stats
-
Sep 21, 1993
Grant Date -
N/A
app pub date -
Oct 25, 1991
filing date -
Dec 26, 1986
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A process for the production of eicosapentaenoic acid comprising the steps of a) culturing a microorganism capable of producing lipid containing eicosapentaenoic acid belonging to a genus selected from the group of Pseudomonas, Alteromonas and Shewanella, to produce lipid containing eicosapentaenoic acid, and b) recovering the eicosapentaenoic acid from the cultured product; a process for production of a lipid containing eicosapentaenoic acid comprising the steps of a) culturing a microorganism capable of producing lipid containing eicosapentaenoic acid belonging to a genus selected from the group of Pseudomonas, Alteromonas and Shewanella, to produce lipid containing eicosapentaenoic acid, and b) recovering the lipid containing eicosapentaenoic acid; and microorganisms capable of producing eicosapentaenoic acid belonging to a genus selected from the group consisting of Pseudomonas, Alteromonas, and Shewanella.

First Claim
Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | Total Patents |
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SAGAMI CHEMICAL RESEARCH CENTER | TOKYO | 36 |
International Classification(s)

- [Classification Symbol]
- [Patents Count]
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Araki, Keiko | Machida, JP | 1 | 72 |
Kondo, Kiyosi | Yamato, JP | 16 | 283 |
Numao, Naganori | Sagamihara, JP | 7 | 97 |
Okazaki, Noriko | Rockville, MD | 4 | 87 |
Yazawa, Kazunaga | Sagamihara, JP | 15 | 276 |
Cited Art Landscape
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Patent Citation Ranking
Forward Cite Landscape
Patent Info | (Count) | # Cites | Year |
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9924733 Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof | 0 | 2010 | |
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6180602 Human novel cDNA, TGF-beta superfamily protein encoded thereby and the use of immunosuppressive agent | 13 | 1997 | |
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* 5569596 Method for bacterial reduction of chromium (VI) | 5 | 1995 | |
* 5739028 Chromium (VI)-resistant strain of Shewanella alga | 4 | 1995 | |
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8685679 Acyltransferase regulation to increase the percent of polyunsaturated fatty acids in total lipids and oils of oleaginous organisms | 0 | 2005 | |
* 2006/0094,088 Acyltransferase regulation to increase the percent of polyunsaturated fatty acids in total lipids and oils of oleaginous organisms | 81 | 2005 | |
7932077 High eicosapentaenoic acid producing strains of Yarrowia lipolytica | 13 | 2005 | |
* 2006/0115,881 High eicosapentaenoic acid producing strains of Yarrowia lipolytica | 60 | 2005 | |
8323935 for high eicosapentaenoic acid production | 4 | 2008 | |
* 2009/0093,543 OPTIMIZED STRAINS OF YARROWIA LIPOLYTICA FOR HIGH EICOSAPENTAENOIC ACID PRODUCTION | 18 | 2008 | |
8518674 English Title Not Available | 0 | 2010 | |
* 2011/0086,919 HIGH EICOSAPENTAENOIC ACID PRODUCING STRAINS OF YARROWIA LIPOLYTICA | 1 | 2010 | |
8735108 for high eicosapentaenoic acid production | 0 | 2012 | |
8815566 English Title Not Available | 0 | 2013 | |
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7566554 PUFA polyketide synthase systems and uses thereof | 0 | 2007 | |
* 2008/0038,379 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 48 | 2007 | |
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* 6140486 Production of polyunsaturated fatty acids by expression of polyketide-like synthesis genes in plants | 110 | 1998 | |
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6566583 Schizochytrium PKS genes | 93 | 1999 | |
7247461 Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof | 50 | 2002 | |
* 2002/0194,641 PUFA polyketide synthase systems and uses thereof | 22 | 2002 | |
7214853 Schizochytrium PKS genes | 65 | 2002 | |
* 2003/0101,486 Schizochytrium PKS genes | 25 | 2002 | |
7211418 PUFA polyketide synthase systems and uses thereof | 76 | 2004 | |
* 2004/0235,127 PUFA polyketide synthase systems and uses thereof | 18 | 2004 | |
7217856 PUFA polyketide synthase systems and uses thereof | 73 | 2004 | |
* 2005/0100,995 PUFA polyketide synthase systems and uses thereof | 19 | 2004 | |
7259295 PUFA polyketide synthase systems and uses thereof | 50 | 2005 | |
7256022 Pufa polyketide synthase systems and uses thereof | 50 | 2005 | |
7256023 PUFA polyketide synthase systems and uses thereof | 52 | 2005 | |
* 2005/0273,883 Pufa polyketide synthase systems and uses thereof | 18 | 2005 | |
* 2005/0266,440 PUFA polyketide synthase systems and uses thereof | 17 | 2005 | |
7271315 PUFA polyketide synthase systems and uses thereof | 72 | 2006 | |
8829274 Schizochytrium PKS genes | 1 | 2007 | |
* 2009/0098,622 SCHIZOCHYTRIUM PKS GENES | 6 | 2007 | |
7642074 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
* 2007/0256,146 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 46 | 2007 | |
7759548 Polyunsaturated fatty acid production in heterologous organisms using PUFA polyketide synthase systems | 6 | 2007 | |
* 2007/0270,494 POLYUNSATURATED FATTY ACID PRODUCTION IN HETEROLOGOUS ORGANISMS USING PUFA POLYKETIDE SYNTHASE SYSTEMS | 72 | 2007 | |
* 2007/0244,192 PLANT SEED OILS CONTAINING POLYUNSATURATED FATTY ACIDS | 75 | 2007 | |
7939716 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
7906706 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
7902427 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
7803620 Pufa polyketide synthase systems and uses thereof | 4 | 2007 | |
7626009 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
7601522 PUFA polyketide synthase systems and uses thereof | 7 | 2007 | |
* 2008/0026,434 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 44 | 2007 | |
* 2008/0026,437 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 28 | 2007 | |
* 2008/0026,435 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 44 | 2007 | |
* 2008/0026,436 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 28 | 2007 | |
* 2007/0266,455 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 28 | 2007 | |
7960524 PUFA polyketide synthase systems and uses thereof | 3 | 2007 | |
7842796 PUFA polyketide synthase systems and uses thereof | 3 | 2007 | |
7816504 PUFA polyketide synthase systems and uses thereof | 3 | 2007 | |
7608703 PUFA polyketide synthase systems and uses thereof | 5 | 2007 | |
7608702 PUFA polyketide synthase systems and uses thereof | 5 | 2007 | |
* 2008/0038,790 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 36 | 2007 | |
* 2008/0026,440 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 38 | 2007 | |
* 2008/0026,438 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 36 | 2007 | |
8003772 Chimeric PUFA polyketide synthase systems and uses thereof | 13 | 2007 | |
7897844 PUFA polyketide synthase systems and uses thereof | 3 | 2007 | |
7973149 PUFA polyketide synthase systems and uses thereof | 3 | 2007 | |
7919320 PUFA polyketide synthase systems and uses thereof | 3 | 2007 | |
7807442 PUFA polyketide synthase systems and uses thereof | 3 | 2007 | |
7605245 PUFA polyketide synthase systems and uses thereof | 5 | 2007 | |
* 2008/0044,867 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 38 | 2007 | |
* 2008/0038,791 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 37 | 2007 | |
7847077 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
7838649 PUFA polyketide synthase systems and uses thereof | 3 | 2007 | |
7816505 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
* 2010/0099,154 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 2 | 2007 | |
7662597 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
7645597 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
7645598 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
7638315 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
7611874 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
7611875 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
7608753 PUFA polyketide synthase systems and uses thereof | 6 | 2007 | |
7563603 PUFA polyketide synthase systems and uses thereof | 6 | 2007 | |
7563604 PUFA polyketide synthase systems and uses thereof | 6 | 2007 | |
7563605 PUFA polyketide synthase systems and uses thereof | 6 | 2007 | |
* 2008/0050,790 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
* 2008/0044,869 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
* 2008/0044,873 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 44 | 2007 | |
* 2008/0038,797 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 44 | 2007 | |
* 2008/0038,793 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 44 | 2007 | |
* 2008/0038,796 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
* 2008/0038,795 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 44 | 2007 | |
* 2008/0040,822 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 50 | 2007 | |
7897391 PUFA polyketide synthase systems and uses thereof | 3 | 2007 | |
7897392 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
7897393 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
7879608 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
7799564 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
7718431 PUFA polyketide synthase systems and uses thereof | 3 | 2007 | |
7629450 PUFA polyketide synthase systems and uses thereof | 4 | 2007 | |
7560539 PUFA polyketide synthase systems and uses thereof | 7 | 2007 | |
* 2008/0050,791 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 28 | 2007 | |
* 2008/0038,798 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 28 | 2007 | |
* 2008/0032,368 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 26 | 2007 | |
* 2008/0032,338 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 28 | 2007 | |
* 2008/0032,369 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 28 | 2007 | |
* 2008/0032,367 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 28 | 2007 | |
8207363 Thraustochytrids, fatty acid compositions, and methods of making and uses thereof | 4 | 2009 | |
* 2010/0239,533 Thraustochytrids, Fatty Acid Compositions, and Methods of Making and Uses Thereof | 3 | 2009 | |
8940884 Polyunsaturated fatty acid synthase nucleic acid molecules and polypeptides, compositions, and methods of making and uses thereof | 0 | 2010 | |
* 2010/0266,564 Polyunsaturated Fatty Acid Synthase Nucleic Acid Molecules and Polypeptides, Compositions, and Methods of Making and Uses Thereof | 7 | 2010 | |
* 2011/0177,031 Eicosapentaenoic Acid-Producing Microorganisms, Fatty Acid Compositions, and Methods of Making and Uses Thereof | 1 | 2010 | |
8426686 Polyunsaturated fatty acid production in heterologous organisms using PUFA polyketide synthase systems | 1 | 2010 | |
* 2011/0167,508 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 5 | 2010 | |
8309796 Chimeric PUFA polyketide synthase systems and uses thereof | 0 | 2011 | |
9222112 Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof | 1 | 2012 | |
8859855 Chimeric PUFA polyketide synthase systems and uses thereof | 0 | 2012 | |
9382521 Polyunsaturated fatty acid production in heterologous organisms using PUFA polyketide synthase systems | 0 | 2013 | |
9611488 Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof | 0 | 2015 | |
9668499 Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof | 0 | 2015 | |
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* 2007/0245,431 POLYUNSATURATED FATTY ACID PRODUCTION IN HETEROLOGOUS ORGANISMS USING PUFA POLYKETIDE SYNTHASE SYSTEMS | 80 | 2007 | |
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7611876 PUFA polyketide synthase systems and uses thereof | 3 | 2007 | |
* 2008/0044,870 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 44 | 2007 |
Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
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Fee | Large entity fee | small entity fee | micro entity fee |
---|---|---|---|
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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