Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties

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United States of America Patent

PATENT NO 5246943
SERIAL NO

07885263

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Abstract

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This invention relates to novel substituted 1,2,3,4-tetrahydroisoquinolines which are useful in the treatment of vascular restenosis, various disorders of the central nervous system, in the regulation of female reproductive functions, in cognitive enhancement, in atherosclerosis and in treating excessive AVP secretory disorders. Novel intermediates useful in the preparation of the compounds are also disclosed. Methods of using the compounds and pharmaceutical compositions containing them are disclosed.

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Patent Owner(s)

Patent OwnerAddress
WARNER-LAMBERT COMPANY2800 PLYMOUTH ROAD ANN ARBOR MICHIGAN 48105 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blankley, Clifton J Ann Arbor, MI 7 155
Hodges, John C Ann Arbor, MI 35 807
Klutchko, Sylvester Ann Arbor, MI 15 366

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