Polymeric carriers for non-covalent drug conjugation
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United States of America Patent
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Oct 12, 1993
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N/A
app pub date -
Sep 23, 1988
filing date -
Sep 23, 1988
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Expired
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Abstract
Polymeric carriers are polypeptides comprising at least one drug-binding domain that non-covalently binds a drug. A polymeric carrier may be attached to an antibody specific for desired target cells to form immunoconjugates that deliver a drug to the target cells in vivo. The carriers are derived from drug-binding proteins and produced through peptide synthesis or recombinant DNA technology.
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