Flourescence intramolecular energy transfer conjugate compositions and detection methods

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United States of America Patent

PATENT NO 5254477
SERIAL NO

07762245

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Abstract

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A variety of conjugated compositions and methods for the detection of an analyte of interest in a fluid sample is provided which relies upon an intramolecular energy transfer between a conjugated fluorophore and a chromophoric light-absorbing ligand for qualitative and quantitative results. The detection methods preferably employ fiber optic sensors in combination with analyte-insensitive fluorophores and analyte-sensitive absorber ligands in conjugated form. The methods and compositions rely upon the ability of the absorbing ligands to absorb energy which is transferred non-radiatively by the fluorophore when in an excited state.

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Patent Owner(s)

Patent OwnerAddress
TRUSTEES OF TUFTS COLLEGEBALLOU HALL MEDFORD MA 02155

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Walt, David R Lexington, MA 119 10740

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