Semi-synthesis of taxane derivatives using metal alkoxides and oxazinones
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United States of America Patent
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Oct 19, 1993
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Apr 6, 1992
filing date -
Apr 6, 1992
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Abstract
A process for preparing taxane derivatives taxol by providing a metal alkoxide having the bi, tri-, or tetracyclic taxane nucleus, reacting the metal alkoxide with an oxazinone to form an intermediate, and converting the intermediate to the taxane derivative.
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