Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof
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United States of America Patent
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Oct 26, 1993
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N/A
app pub date -
Sep 24, 1990
filing date -
Apr 1, 1988
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Expired
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Abstract
The present invention relates to compositions comprising soluble complement receptor 1 (CR1) and a thrombolytic agent. In a specific embodiment, the thrombolytic agent is anisoylated human plasminogen-streptokinase activator complex (ASPAC). The invention further relates to methods for treating thrombotic conditions in humans and animals by administering a composition comprising soluble CR1 and a thrombolytic agent. In particular, the compositions and methods are useful both for reducing reperfusion injury and ameliorating the other effects of myocardial infarction.
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