27-hydroxyrapamycin and derivatives thereof
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United States of America Patent
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Oct 26, 1993
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N/A
app pub date -
Jan 27, 1993
filing date -
Aug 13, 1992
priority date (Note) -
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Abstract
This invention provides a compound of formula I, ##STR1## and 27-substituted derivatives thereof which are useful as immunosuppressive, antiinflammatory, antifungal, antitumor, and antiproliferative agents. The compound depicted by formula I is named 27-hydroxyrapamycin, and may also be referred to as 27-deoxo-27-hydroxyrapamycin.
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